The U.S. Environmental Protection Agency's (EPA) decision to sideline its independent chemical referee, the Integrated Risk Information System (IRIS), is a move that could have dire consequences for public health. This program, which has been a cornerstone of chemical safety assessment for decades, is now being dismantled by the Trump administration, opening the door for political pressure and potentially endangering the public. What makes this particularly fascinating is the historical context and the implications of this decision. From my perspective, the IRIS program has been a beacon of scientific integrity, providing a neutral and evidence-based approach to assessing chemical hazards. It has set the standard for chemical hazard assessments internationally, and its dismantling raises a deeper question about the role of science in policy-making. The IRIS program was a unique and invaluable resource, providing a comprehensive and transparent assessment of chemical hazards. It was developed over four decades, with scientists rigorously reviewing and updating assessments to reflect the latest research. This process was designed to ensure that scientific judgments were grounded in evidence, not in policy preferences or financial interests. However, some industry-aligned organizations have argued that IRIS assessments are flawed or biased, calling for their elimination. In my opinion, these claims are baseless and have been repeatedly debunked by independent scientific reviews. The IRIS program was not just a scientific endeavor; it was a critical tool for ensuring that public health was protected. By sidelining IRIS, the EPA is essentially removing a neutral and evidence-based approach to chemical safety assessment. This shift risks undermining the foundation of scientific integrity that has underpinned environmental policy for decades. The consequences of this decision could be far-reaching, with prolonged litigation and delays in developing or implementing regulations, potentially with real consequences for public health. What makes this situation especially concerning is the historical context. The IRIS program has been a trusted source of information for decades, providing a clear and well-documented scientific record that courts have generally given weight to. By dismantling IRIS, the EPA is essentially throwing out the baby with the bathwater, potentially weakening the scientific foundation of environmental policy. In conclusion, the dismantling of the IRIS program is a worrying development that could have serious implications for public health. It is a reminder of the importance of scientific integrity and the need to protect it from political pressure. Personally, I believe that independent referees are essential to ensuring that facts are determined by evidence, not by the industries that would benefit. As we move forward, it is crucial to reflect on the implications of this decision and work to protect the scientific foundation of environmental policy.